Product Information

Product name: Anti-FSH beta/FSHB Antibody Picoband® (PE Conjugate)

Catalog number: 0519-PB9106-PE

Size: 100 µg/vial

Target: Follicle-stimulating hormone beta (FSHB)

Species reactivity: Human, Mouse (as reported for the antibody)

Conjugate: Phycoerythrin (PE)

Reported applications: IHC, WB; confirm suitability of the PE-conjugated format for the intended assay with the current product datasheet.

Dry ice: No

Hazardous shipping: No

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

What Is FSHB?

Follicle-stimulating hormone beta (FSHB) is the beta subunit of follicle-stimulating hormone (FSH), a glycoprotein hormone involved in reproductive function. FSH is produced by the anterior pituitary gland and acts through its receptor to regulate important processes in the ovaries and testes.

The FSHB gene encodes the beta subunit, which contributes to the biological specificity of FSH. Together with the hormone's alpha subunit, FSH beta forms the functional hormone involved in reproductive signaling.

Biological Functions of Follicle-Stimulating Hormone

FSH plays important roles in both female and male reproductive physiology. In the ovaries, it supports the growth and development of ovarian follicles and promotes the function of granulosa cells. In the testes, it acts on Sertoli cells, contributing to their function and supporting spermatogenesis.

Because FSH activity is essential to reproductive processes, the FSHB gene and its protein product are studied in research investigating hormone regulation, reproductive development, fertility biology, and endocrine signaling.

Key Product Features

• Defined molecular target: Designed to recognize FSH beta/FSHB, according to the supplied product information.
• PE conjugation: Phycoerythrin is a fluorescent label commonly used for fluorescence-based detection.
• Reported species reactivity: Human and mouse.
• Research applications: The product listing reports immunohistochemistry (IHC) and Western blot (WB); verify the application details for the conjugated format before use.
• Convenient format: Supplied as 100 µg per vial.

Understanding the PE Conjugate

Phycoerythrin (PE) is a fluorescent phycobiliprotein used as a label in immunological detection methods. Its fluorescence can help researchers visualize antibody binding when the conjugate is compatible with the assay, instrument, and sample preparation method.

PE-conjugated antibodies are frequently used in fluorescence-based assays, including flow cytometry and fluorescence microscopy, when the specific antibody product is validated for those applications. Do not assume that every PE-conjugated antibody is suitable for every technique; consult the current product datasheet for validated uses, recommended conditions, and detection settings.

Research Applications

• Research on FSH beta expression and reproductive hormone biology.
• Investigation of ovarian follicle development and granulosa cell function.
• Studies of Sertoli cell biology and spermatogenesis.
• Research into pituitary hormone regulation and endocrine signaling.
• Protein detection studies using only applications confirmed for this specific antibody format.

Technical Specifications

Handling and Experimental Considerations

• Consult the current datasheet for storage temperature, reconstitution, and handling instructions.
• Protect the fluorescent conjugate from unnecessary exposure to light.
• Use appropriate positive and negative controls to assess signal specificity.
• Optimize staining, washing, and detection conditions for the sample type and assay.
• Confirm that the selected protocol is validated for the PE-conjugated product rather than relying solely on information for an unconjugated antibody.

Frequently Asked Questions

What does FSHB stand for?

FSHB stands for follicle-stimulating hormone subunit beta, the beta subunit of the hormone FSH.

What is the biological role of FSH?

FSH contributes to ovarian follicle development in females and supports Sertoli cell function and spermatogenesis in males.

What is the purpose of PE conjugation?

PE provides a fluorescent signal that can help researchers detect antibody binding in compatible fluorescence-based assays.

Which applications are reported for this antibody?

The supplied product description reports IHC and Western blot. Check the current technical datasheet to confirm which methods are validated for the PE-conjugated format.