FLUORESCENTLY LABELED ANTIBODIES

Cystatin A (CSTA/2882), CF568 Conjugate

Fluorescent Conjugate | 0.1 mg/mL | CSTA Protein Detection

Product Description

Cystatin A (CSTA), also known as Stefin A, is a member of the cystatin superfamily of proteins. It belongs to the type 1 cystatin family and functions primarily as an endogenous inhibitor of cysteine proteases.

Cystatin A forms tight inhibitory complexes with several cysteine proteases, including papain and cathepsins B, H and L. Through this activity, it contributes to the regulation of proteolytic processes involved in cellular function and tissue homeostasis.

CSTA is particularly associated with epithelial tissues and is an important precursor component of the cornified cell envelope in keratinocytes. It plays a role in epidermal development, differentiation and maintenance of the skin barrier.

This CF568-conjugated Cystatin A reagent is designed for fluorescent detection of the CSTA target in research applications. CF568 fluorescent labeling provides a bright signal suitable for fluorescence-based protein detection and cellular localization studies.

Fluorescently labeled reagents can support investigations of protein distribution, tissue expression and biological pathways associated with cysteine protease regulation.

Key Features

• Target: Cystatin A (CSTA / Stefin A).
• Identifier: 2882.
• CF568 fluorescent conjugate.
• Concentration: 0.1 mg/mL.
• Supplied in a 500 µL format.
• Suitable for fluorescence-based research applications.
• Supports studies of cysteine protease regulation.
• Useful for investigating CSTA expression and localization.

Biological Function of Cystatin A

Cystatin A belongs to the type 1 cystatin family, also known as stefins. These proteins are generally intracellular inhibitors of cysteine proteases.

Its biological functions include:

• Protease Inhibition: Regulation of cysteine protease activity, including cathepsins.
• Epidermal Development: Participation in keratinocyte differentiation and skin barrier formation.
• Cellular Homeostasis: Contribution to the balance of proteolytic activity within cells and tissues.
• Protein Regulation: Involvement in biological processes controlled by cysteine protease activity.

Applications

• Fluorescence Microscopy: Investigation of Cystatin A distribution and localization.
• Protein Expression Studies: Analysis of CSTA expression in biological samples.
• Cell Biology: Research into epithelial cell differentiation and function.
• Skin Biology: Investigation of epidermal development and skin barrier maintenance.
• Protease Research: Studies of cysteine protease inhibition and regulation.
• Cancer Research: Investigation of the potential relationship between cystatin expression and disease biology.

CF568 Fluorescent Label

CF568 is a red fluorescent dye used for fluorescent labeling in biological research. CF568-conjugated reagents provide a fluorescent signal that can be detected using compatible fluorescence imaging systems.

Fluorescent labeling facilitates visualization of target distribution and supports protein localization experiments in cells and tissues.

• Red fluorescent labeling for microscopy-based detection.
• Suitable for fluorescence imaging workflows.
• Supports protein localization and expression studies.
• Can be incorporated into multicolor fluorescence experiments when compatible detection channels are available.

Select appropriate fluorescence excitation and emission settings according to the CF568 dye specifications and the instrument manufacturer's recommendations.

Technical Specifications

Product Name: Cystatin A (CSTA/2882), CF568 Conjugate

Catalog Number: 0037-BNC682882-500

Target: Cystatin A (CSTA)

Gene Symbol: CSTA

Identifier: 2882

Fluorescent Conjugate: CF568

Concentration: 0.1 mg/mL

Size: 1 × 500 µL

CAS Number: 9007-83-4

Dry Ice: No

Hazardous: No

Research Applications of Cystatin A

Cystatin A is an important research target in studies involving protease regulation, epidermal biology and epithelial tissue function.

Its interaction with cysteine proteases and its involvement in keratinocyte differentiation make it relevant to investigations of skin physiology, cellular homeostasis and disease-associated protein expression.

Fluorescent detection approaches can help researchers investigate the distribution and localization of CSTA in experimental biological systems.

Looking for Fluorescently Labeled Research Reagents?

Discover research solutions for protein detection, fluorescence microscopy and cell biology.