Life Science

Life Science

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  • Midostaurin | HY-10230

    Midostaurin | HY-10230

    Gentaur

    Midostaurin | HY-10230 Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr,...
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  • Mirdametinib | HY-10254

    Mirdametinib | HY-10254

    Gentaur

    Mirdametinib | HY-10254 Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated...
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  • AG1024 | HY-10253

    AG1024 | HY-10253

    Gentaur

    AG1024 | HY-10253 AG1024 (Tyrphostin AG 1024) is a reversible, competitive and selective IGF-1R inhibitor with an IC50 of 7 μM. AG1024 inhibits phosphorylation of IR (IC50=57 μM). AG1024 induces...
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  • NVP-ADW742 | HY-10252

    NVP-ADW742 | HY-10252

    Gentaur

    NVP-ADW742 | HY-10252 NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM...
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  • AKT Kinase Inhibitor | HY-10249A

    AKT Kinase Inhibitor | HY-10249A

    Gentaur

    AKT Kinase Inhibitor | HY-10249A AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity[1]. IC50 & Target : Akt In Vitro: The effect of selective inhibition of Akt in proliferating...
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  • GSK-690693 | HY-10249

    GSK-690693 | HY-10249

    Gentaur

    GSK-690693 | HY-10249 GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects...
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  • BRAF inhibitor | HY-10247

    BRAF inhibitor | HY-10247

    Gentaur

    BRAF inhibitor | HY-10247 BRAF inhibitor is a B-Raf inhibitor extracted from patent WO/2011103196 A1, Compound P-0850. IC50 & Target : B-Raf Molecular weight: 456.47 Formula: C22H18F2N4O3S SMILES:
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  • Sunitinib | HY-10255A

    Sunitinib | HY-10255A

    Gentaur

    Sunitinib | HY-10255A Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib, an ATP-competitive...
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  • Adezmapimod | HY-10256

    Adezmapimod | HY-10256

    Gentaur

    Adezmapimod | HY-10256 Adezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod inhibits...
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  • Adezmapimod hydrochloride | HY-10256A

    Adezmapimod hydrochloride | HY-10256A

    Gentaur

    Adezmapimod hydrochloride | HY-10256A Adezmapimod (SB 203580) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2,...
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  • PD 123319 ditrifluoroacetate | HY-10259A

    PD 123319 ditrifluoroacetate | HY-10259A

    Gentaur

    PD 123319 ditrifluoroacetate | HY-10259A PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. IC50 & Target : IC50: 34 nM (AT2...
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