Life Science

Avibactam sodium hydrate | HY-14879B Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1]...

Remdesivir | HY-104077 Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly...

Mevalonic acid lithium salt | HY-113071A Mevalonic acid lithium salt, a precursor in the mevalonate pathway, is essential for cell growth and proliferation. IC50 & Target: Human Endogenous...

IWP-2 | HY-13912 IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive...

Brigatinib | HY-12857 Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor, with an IC50 of 0.6 nM[1]. IC50 & Target: IC50: 0.6 nM (ALK) In Vitro: Brigatinib potently inhibits the in vitro kinase activity of ALK (IC50, 0.6 nM)...

Y-27632 dihydrochloride | HY-10583 Y-27632 dihydrochloride is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 dihydrochloride attenuates Doxorubicin-induced apoptosis of human cardiac...

BI-D1870 | HY-10510 BI-D1870 is an ATP-competitive, cell permeable and brain penetrated inhibitor of RSK isoforms, with IC50s of 31 nM/24 nM/18 nM/15 nM for RSK1/RSK2/RSK3/RSK4, respectively. IC50 & Target: IC50: 31 nM (RSK1), 24 nM (RSK2), 18...

Laduviglusib CHIR-99021 | HY-10182   Laduviglusib (CHIR-99021) is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases...

Navitoclax | HY-10087 Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-xL, Bcl-2 and Bcl-w, with a Ki of less than 1...

PROTEOSAVE 1.5mL Microtube | MS-4215MZ PROTEOSAVE™ series products have a unique high hydrophilic polymer surface treatment. The tube and well surface are coated with a high-density hydroxyl group which blocks the non-specific binding of proteins,...

PROTEOSAVE 0.5mL Microtube, radiation | MS-4255MZ PROTEOSAVE™ series products have a unique high hydrophilic polymer surface treatment. The tube and well surface are coated with a high-density hydroxyl group which blocks the non-specific binding of...

Lock Stand for Cryogenic Vial | MS-78000Z The cryogenic vials can be fixed in each well by special meshing design of the Lock Stand allowing for one-hand screwing of the vial cap. Polypropylene Cryogenic Vial Lock Stand, 30 Vials. Can be submerged,...