3CLglow Assay Kit | C1160G

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3CLglow Assay Kit | C1160G

A live cell assay for SARS-CoV-2 3CLpro enzyme activity and inhibition.

3CLpro (Mpro) Inhibitor Assay

The 3CLglow Assay kit includes 2 BacMam viruses. One expresses the 3CLpro enzyme, the other expresses a green fluorescent biosensor for 3CLpro enzyme activity as well as a red fluorescent protein to control for compound toxicity.

  • Identify protease inhibitors that target SARS-CoV-2 replication
  • Cost effective screening with minimal safety requirements (BSL-1)

Materials in the Kit:

• Green Fluorescent 3CLpro reporter in BacMam (3CLglow BacMam)

• 3CLpro Enzyme in BacMam

• Sodium Butyrate, 500 mM in H2O

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