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Description
3CLglow Assay Kit | C1160G
A live cell assay for SARS-CoV-2 3CLpro enzyme activity and inhibition.
3CLpro (Mpro) Inhibitor Assay
The 3CLglow Assay kit includes 2 BacMam viruses. One expresses the 3CLpro enzyme, the other expresses a green fluorescent biosensor for 3CLpro enzyme activity as well as a red fluorescent protein to control for compound toxicity.
- Identify protease inhibitors that target SARS-CoV-2 replication
- Cost effective screening with minimal safety requirements (BSL-1)
Materials in the Kit:
• Green Fluorescent 3CLpro reporter in BacMam (3CLglow BacMam)
• 3CLpro Enzyme in BacMam
• Sodium Butyrate, 500 mM in H2O