CD28 Antibody | ANT-271

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SKU:
PS-ANT-271
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Description

CD28 Antibody | ANT-271

Hamster Anti Mouse Monoclonal.

INTRODUCTION

CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence.

CLONE

NYRmCD28.

IMMUNOGEN

Purified mouse purified mouse LN T cells.

IG SUBCLASS

Hamster IgG.

PURIFICATION METHOD

Protein-A.

FORMULATION

1mg/ml in PBS (after reconstitution).

STORAGE PROCEDURES

Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

SOLUBILITY

Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

APPLICATIONS

Blocking and staining antibody. For staining, use 10µl/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator.

AVAILABLE CONJUGATES

This antibody is only available conjugated to Biotin and FITC.

USAGE

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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