Frequently bought together:
Description
BRAF inhibitor | HY-10247
BRAF inhibitor is a B-Raf inhibitor extracted from patent WO/2011103196 A1, Compound P-0850.
IC50 & Target :
B-Raf
Molecular weight:
456.47
Formula:
C22H18F2N4O3S
SMILES:
CC(C)S(=O)(NC1=CC=C(C(C(C2=CNC3=NC=C(C=C32)C4=CC=CN=C4)=O)=C1F)F)=O
Storage:
Related Products
AKT Kinase Inhibitor | HY-10249A
Gentaur
AKT Kinase Inhibitor | HY-10249A
AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity[1].
IC50 & Target :
Akt
In Vitro:
The effect of selective inhibition of Akt in...
Danoprevir | HY-10238
Gentaur
Danoprevir | HY-10238
Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases...
Sunitinib | HY-10255A
Gentaur
Sunitinib | HY-10255A
Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively[1]. Sunitinib, an ATP-competitive...
Panobinostat | HY-10224
Gentaur
Panobinostat | HY-10224
Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities. Panobinostat induces HIV-1 virus production...
Adezmapimod | HY-10256
Gentaur
Adezmapimod | HY-10256
Adezmapimod (SB 203580) is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. Adezmapimod inhibits...
Bortezomib | HY-10227
Gentaur
Bortezomib | HY-10227
Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts...
Ixabepilone | HY-10222
Gentaur
Ixabepilone | HY-10222
Ixabepilone (BMS-247550) is an orally bioavailable microtubule inhibitor, which binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby...
Luminespib | HY-10215
Gentaur
Luminespib | HY-10215
Luminespib (VER-52296) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90α and HSP90β, respectively.
IC50 & Target:
Remdesivir | HY-104077
Gentaur
Remdesivir | HY-104077
Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus...