SARS-CoV-2 Spike Glycoprotein Antibody | abx376478

SARS-CoV-2/COVID-19 Spike Glycoprotein Antibody is a chimaeric recombinant Monoclonal antibody expressed in CHO cells against SARS-CoV-2 Spike Glycoprotein, containing Mouse variable region and Human IgG1 Kappa constant region.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

Target: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Glycoprotein
Clonality: Monoclonal
Reactivity: Virus
Origin: Human
Expression: Recombinant
Tested Applications: ELISA, WB
Host: Human, Mouse
Recommended dilutions: ELISA: 1/5000 - 1/10000, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation: Unconjugated
Immunogen: Recombinant SARS-CoV-2 S1 protein.
Isotype: IgG1 Kappa
Form: Liquid
Purification: Purified by affinity chromatography.
Storage: Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.